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The recombinant antigen used to make PROVENGE is PAP-GM-CSF. It consists of prostatic acid phosphatase (PAP), an antigen expressed in more than 95% of prostate cancers, and granulocyte-macrophage colony-stimulating factor (GM-CSF), an immune-cell activator.1
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PRV.0136.USA.16-PXA0015 USA 16 v1.1